In today’s fast-paced world, where heart disease remains the leading cause of death in the U.S., many are turning to nature’s medicine cabinet in search of safer, more effective ways to protect their cardiovascular health. While aspirin has long been hailed as a go-to for heart attack and stroke prevention, new research reveals that one specific food may offer even greater benefits—without the risks.
So, what’s the best food for heart health, one that can naturally support clean arteries, prevent blood clots, and lower your risk of cardiovascular events?
Let’s explore the science behind this powerful nutrient-dense food—and why it might just deserve a permanent place in your daily wellness routine.

Understanding Blood Clots and Cardiovascular Risk
Roughly 80% of heart attacks and strokes result not from gradual cholesterol buildup alone, but from the sudden formation of a blood clot, which blocks an artery. These clots often form when unstable arterial plaque ruptures, triggering platelets to rush to the site and clump together—like superglue—cutting off blood flow to the heart or brain.
Aspirin works by thinning the blood and preventing these platelets from clumping. For decades, low-dose aspirin was widely recommended for adults over 60. However, after 2022, guidelines shifted due to potential risks, including gastrointestinal bleeding and hemorrhagic stroke. While aspirin has undoubtedly saved lives, it comes with side effects—not everyone tolerates it well.
So the question is: Can we achieve similar—or even superior—protective effects through food?
Enter Omega-3 Fatty Acids: Nature’s Blood-Thinning Super Nutrient
One nutrient, backed by extensive clinical evidence, has been shown to reduce clot formation, stabilize arterial plaques, and lower inflammation: omega-3 fatty acids, particularly EPA (eicosapentaenoic acid).
You may be familiar with omega-3s from fish oil supplements, but let’s get specific. While both EPA and DHA (docosahexaenoic acid) are beneficial, research points to EPA as the true game-changer when it comes to heart health.

What Makes EPA So Powerful?
- Reduces platelet aggregation (platelets become less sticky, lowering clot risk)
- Stabilizes arterial plaques, making them less likely to rupture
- Reduces inflammation, a major driver of heart disease
- Lowers cortisol and adrenaline, stress hormones linked to morning heart attacks
In fact, a clinical trial published in the New England Journal of Medicine (REDUCE-IT Study, 2019) showed that high-dose purified EPA reduced major cardiovascular events by 25%, including heart attacks, strokes, and cardiac deaths.
And unlike aspirin, EPA has no known serious side effects.
Why Cod Liver Oil May Be the Best Food for Arterial Health
While many cold-water fatty fish like salmon, mackerel, and sardines are excellent sources of EPA, cod liver oil stands out as the single best food to support clean arteries and prevent heart disease naturally.
Here’s why cod liver oil earns its reputation as a cardiovascular superfood:
1. Rich in EPA
Cod liver oil delivers a highly concentrated dose of EPA, making it one of the best natural blood thinners available without a prescription.
2. Provides Preformed Vitamin A (Retinol)
This fat-soluble vitamin plays a crucial role in maintaining and repairing the inner lining of blood vessels (the endothelial layer). Retinol also exhibits powerful anti-inflammatory properties, which further protect against atherosclerosis (plaque buildup).
3. High in Vitamin D
Vitamin D helps improve arterial flexibility, enhances nitric oxide production (which supports healthy blood pressure), and stabilizes plaques. In one study evaluating 1,000 compounds, vitamin D was the most effective at protecting the inner arterial walls from damage.

Vitamin D also works synergistically with vitamin K2 to prevent arterial calcification, a hallmark of advanced heart disease.
4. Natural Mood Support
EPA is also known for its ability to reduce symptoms of anxiety and depression—thanks to its effect on cortisol and adrenaline levels. Considering that psychological stress is a well-known risk factor for cardiovascular events (think “broken heart syndrome”), this emotional benefit shouldn’t be underestimated.
Cod Liver Oil vs. Aspirin: A Smarter Approach?
Aspirin works by disabling platelet enzymes involved in clotting. However, cod liver oil takes a gentler, more holistic approach. By integrating directly into cell membranes, EPA prevents the inflammatory cascade that makes platelets sticky in the first place. This means you’re addressing the root cause—without the digestive or bleeding complications associated with daily aspirin use.
Warfarin, another prescription blood thinner, blocks vitamin K1—disrupting your body’s natural clotting cascade. But this drug comes with strict dietary restrictions and serious risks if mismanaged.
Cod liver oil, by contrast, supports balance. It helps keep blood flowing smoothly, supports the structural integrity of arteries, and nourishes your body with multiple essential nutrients.
How to Use Cod Liver Oil for Cardiovascular Health
To get the heart-healthy benefits of EPA, here’s how to incorporate cod liver oil safely and effectively:
- Dosage: 1 teaspoon (about 5 mL) of high-quality cod liver oil daily
- Form: Choose liquid or softgel capsules; liquid is often more potent and bioavailable
- Type: Look for wild-caught, cold-pressed cod liver oil from reputable brands. Avoid synthetic additives or oils that have been deodorized or bleached.
- Pair with vitamin K2: Either through supplementation or foods like natto, aged cheese, or grass-fed butter to help direct calcium away from arteries and into bones
Tip: Cod liver itself (available canned) is also an excellent food source, especially when consumed once or twice weekly.

Final Thoughts: A Heart-Smart Addition to Your Diet
There’s no question that cod liver oil offers a natural, multi-functional way to support cardiovascular health—especially for those looking to reduce blood clot risk, manage inflammation, and nourish the body holistically.
While medications like aspirin and warfarin have their place, whole-food solutions with fewer side effects should always be considered as a first line of defense when appropriate. Cod liver oil checks all the boxes—providing EPA, vitamins A and D, and a gentle blood-thinning effect backed by science.
Take the Next Step Toward Heart Health
If you’re looking to optimize your diet for heart health, reduce your risk of stroke or heart attack naturally, or want personalized nutrition strategies for inflammation, weight loss, or disease prevention—consult with a qualified nutritionist or integrative health professional.
Better yet, explore more evidence-based articles and smart food swaps designed to empower your health through science and flavor. Your heart will thank you.